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Ultraviolet radiation (UVR) is a well‐known exacerbating factor for cutaneous lupus erythematosus (CLE), with photosensitivity comprising one of the American College of Rheumatology (ACR) diagnostic criteria for systemic lupus erythematosus (SLE). However, discerning true photosensitivity in this population is difficult due to the broad language utilized by the ACR and the delayed‐onset nature of photosensitive lupus lesions.
Read More: Photosensitivity in cutaneous lupus erythematosus →
Patients who have systemic lupus erythematosus have increased numbers of chromosome breaks and rearrangements correlated with a low molecular weight chromosome-damaging agent that is released from their lymphocytes into the serum.
Read More: Mechanism of photosensitivity in systemic lupus erythematosus patients →
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